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> PCT - The hows and the whats
  
Posted: Dec 27 2005, 08:54 PM
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Bet many of you here are well aware that you defenitely need a PCT after a cycle of something hormonal like 1AD, 1-T, m1t, m5 or even SD. There are any number of threads that tell you to take nolva, 6oxo, clomid, R-Xt. This thread is dedicated for those who are really interested to know why someone asks you to do that PCT and what exactly happens to your body during a PCT.

So why do I need to take all this stuff after my cycle?
During a cycle of AAS, natural production of testosterone decreases, often times to zero. In many cases, the diminished natural testosterone production causes a cessation of sperm production (spermatogenesis), and the male becomes sterile. After the cycle, the body's ability to make testosterone may take months to start again. Aside from the undesirable sterility and loss of strength, other hormone levels get out of whack because of the low testosterone, and cause other problems such as increased body fat and depression. The body produces many hormones, and the levels of most hormones are interrelated. This article will examine the factors involved in regulating the production of certain hormones in the body, particularly by the Hypothalamic-Pituitary-Testicular Axis

So what's the big deal in taking so many different compounds together?

The ideal post cycle therapy consists of a three compound administration which is designed so that there is a primary and secondary LH stimulator which both are maximizing potential early in the duration;
With the addition of an Aromatase Inhibitor, which makes the above possible, the individual will also endure less of an increase in Sex Hormone Binding Globulin, which allows free testosterone levels to reach base line at a much quicker pace. The individual will also see less of a problem in most cases with sexual libido as the bounding SHBG is controlled (to an extent).


Day 1-15 600 MG 6oxo + 100mg Clomid + 40mg Nolva
Day 16-30 300mg 6oxo + 75mg Clomid + 20mg Nolva

Selective estrogen receptor modulators(SERMs) such as Clomiphine and Tamoxifen are selective to which tissues they bind too.

Clomid being selective to the suprapituitary
Tamox is selective to breast, bone, and liver ERs

In studies showing levels of LH, FSH, and Testosterone checked after short durations of tamox, they were either insignificant, or their was an actual drop. I believe this is because tamox selectively works at the mammery(as well as bone and liver), thus taking longer for LH stimulation to occur.
With clomid, benefit to gonadotrophin concentrations, LH, FSH, and serum testosterone can be seen in short periods of 2-6wks. Because of the apparent selective nature of the two, and given our usual PCT duration, clomid is by far superior at LH stimulation than Nolva. Now both is the wise choice for a couple of reasons:

1. Nolva acts as the preventive measure to the estrogen flux occured PC while clomid is the primary LH stimulator(Even more so in the case an AI is not used).
2. If your running a longer PCT, clomid needs to be discontinued after a while as it has been shown to desensitize GnRH, this due, IMO, to it's selective nature to the suprapituitary. In the longer forms of PCT, the clomid will be phased out, leaving Nolva and 6oxo.


So after my PCT what should I expect from my body?


Hormone panel:
Testosterone: normal range 300 - 1200ng/dl
Free testosterone: normal range 8.7 - 25pg/ml
IGF-1: normal range 109-284ng/ml
Estradiol: normal range 5 - 53pg/ml
DHEA-s: normal range 120 - 520ug/dl

Thyroid panel:
T4: normal range 4.5 - 12ug/dl
T3: normal range 2.3 - 4.2pg/ml
TSH: normal range 0.350 - 5.500uIU/ml

Blood Lipid panel:
Total cholesterol: normal healthy range 100 - 199mg/dl
LDL fraction: normal range 0 - 99mg/dl
HDL fraction: normal range 40 - 59mg/dl
Triglycerides: normal range 0 - 149mg/dl
C-reactive protein: > 2mg/l increased risk of MI and stroke
Homocysteine: normal range 6.3 - 15umol/L

Liver function:
Alkaline phosphatase: Normal range 25 - 150IU/L
GGT: normal range 0 - 65IU/L
SGOT: normal range 0 - 40IU/L
SGPT: normal range 0-40IU/L
PSA: normal 0.0 - 4.0ng/ml

Renal function tests:
Creatinine: normal 0.5 - 1.5mg/dl
BUN: normal range 5 - 26mg/dl
Creatinine/BUN ratio: normal 8 - 27

What else can I take with all my ancillaries for a good PCT

Tribulus, ZMA are good to add on a PCT. Ideally you want to start these in the beginning of week 2 when the natural test levels are catching up.

I am not a doctor neither do I give medical advise.I just post what I have researched and obtained. If I am wrong please feel free to correct me.Thx

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Posted: Dec 27 2005, 08:55 PM
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The superdrol approach is a bit different. Here is to all you superdrol users

Some people are also taking these during and after cycle to help with sustaining ones lipid profile.I am no SD expert, just posting from experiences.

Red Yeast Rice- A fermented rice product, that is our best fighter against negative sides form AAS concerning cardiovascular damage. Comprised of nine different monacolins, which are naturally occurring substances that help regulate cholesterol levels. Along with sterols, and monounsaturated fatty acids, it packs a strong punch.

COQ10- Although this is abundant in food sources, I feel it prudent to put on here. Not only does it show to help cardiac function, but it’s also imperative to be used with Red Yeast Rice. Can be used in combination with other cholesterol lowering supplements.

Celery Seed- A powerful anti-oxidant, shown to not only lower blood pressure, but may have cancer fighting properties as well. And there is evidence to show its ability in aiding the liver.

Policosanol- A blend of fatty alcohol’s, shows great promise in its use as beneficial to cardiovascular health, to include the maintenance of healthy lipid profiles. There is also some theory to a synergistic affect with EFA’s.

Important notes:

1)Nolva has a half life of 5 days so its allright to take your 40mg in one shot.

2)Nolva before night. I figured your test levels are boosted during the rest phase.

3) Anabolic Minds suggests this kinda pct

wk1: 40mg Nolva, 25mg RXT, 3 fenugreek caps, DHEA 200mg
wk2: 40mg Nolva, 25mg RXT, 4 fenugreek caps, DHEA 200mg
wk4: 20mg Nolva, 50mg RXT, 5 fenugreek caps, DHEA 100mg
wk4: 20mg Nolva, 50mg RXT, 6 fenugreek caps, DHEA 100mg


You could take 50mg RXT all the way or ramp down instead of up, I am not sure what would work better, but some say ramp down. It wouldn't hurt to ramp up though, estro rebound is not a prob with RXT. The RYR seem to work best w/ 1200mg. If you are more heavily shutdown, start w/ 60mg on the Nolva instead of 40. The Nolva is highly variable from person to person and you may need a differend dose from the next guy.

So if you were to periodically increase with 6oxo instead of R-XT

wk1: 40mg Nolva, 300 6oxo, 3 fenugreek caps, DHEA 200mg
wk2: 40mg Nolva, 300 6oxo, 4 fenugreek caps, DHEA 200mg
wk4: 20mg Nolva, 600 6oxo, 5 fenugreek caps, DHEA 100mg
wk4: 20mg Nolva, 600 6oxo, 6 fenugreek caps, DHEA 100mg


But if you were to ask me for my frank opinion I would highly recommed a ramp down.

wk1: 40mg Nolva, 600 6oxo, 3 fenugreek caps, DHEA 200mg
wk2: 40mg Nolva, 600 6oxo, 4 fenugreek caps, DHEA 200mg
wk4: 20mg Nolva, 300 6oxo, 5 fenugreek caps, DHEA 100mg
wk4: 10mg Nolva, 300 6oxo, 6 fenugreek caps, DHEA 100mg


But the first above mentioned PCT has its merits too. They are

a) Nolva is hard on the liver. One would therefore phase down nolva and give a giver AI dose during PCT.
cool.gif Like I've mentioned above a SERM + AI pct is best for recovery, while your nat. test levels have restarted the AI maintains it.

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Posted: Dec 27 2005, 09:07 PM
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seeing as how U have two week4's Im assuming one is supposed to be week 3?
very informative

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Posted: Dec 27 2005, 09:29 PM
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that was informative. im not taking, nor planning on taking any ph's right now, i just like to learn everything i can before i do try somehting, and from what i read it will take me a couple years yet before im even ready for a ph.
here's my question. during a ph cycle, could takeing zma and tribulus help keep test levels somewhere close to normal (if also continued after a cycle)? also, could taking coq10, ALA and acytl-l-carnitine during and after a cycle help keep lipid changes and liver damage down to a minimum?

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Posted: Dec 27 2005, 10:42 PM
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QUOTE (Superjew18 @ Dec 27 2005, 09:29 PM)
that was informative. im not taking, nor planning on taking any ph's right now, i just like to learn everything i can before i do try somehting, and from what i read it will take me a couple years yet before im even ready for a ph.
here's my question. during a ph cycle, could takeing zma and tribulus help keep test levels somewhere close to normal (if also continued after a cycle)? also, could taking coq10, ALA and acytl-l-carnitine during and after a cycle help keep lipid changes and liver damage down to a minimum?

Proud to see this thread is doing some good smile.gif

To answer you questions...."during a ph cycle, could takeing zma and tribulus help keep test levels somewhere close to normal (if also continued after a cycle)?" NO...AAS/PH/PS will create major changes to your test levels, regardless of these two products.

"also, could taking coq10, ALA and acytl-l-carnitine during and after a cycle help keep lipid changes and liver damage down to a minimum?" Yes(at correct dosages), that is there purpose and it is VERY wise to implement them during PCT.

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