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 I have ADD and was thinking (yes really) of getting this because of what the article said but then I remembered that aspartame is bad for you so I did a "aspartame ADD" search and found this: http://www.sweetpoison.com/phenylalanine.html can someone put my mind to rest as to wether it is safe to take like is it just aspartame or the Phenylalanine that is bad very confusing !!
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>can someone put my mind to rest as to wether it is safe to take like is it just aspartame or the Phenylalanine that is bad Its the aspartame that's bad. When broken down, it makes aspartic acid and methanol in addition to phenylalanine. Aspartic acid is a neurotransmitter that can be very damaging at high levels, but its debatable whether the levels from nutrasweet are high enough. Methanol is very toxic, but the small amount produced is unlikely to cause problems. Phenylalanine is readily broken down into the normal energy-producing molecules your body uses every day.
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This is not what I am reading on the web. Congressional Testimony on Phenylanaline http://www.wnho.net/nutrasweet_testimony.htm| QUOTE | Dr. Pardridge: A second study shows that if you measure choice reaction time, a test of higher cognitive function in humans, that when their bloom phenylalanine is increased six-fold, there is a 10 percent shift in your ability to make a key decision before a video screen.
And a more recent study by Dr. Elsas has shown that there are quantitative changes in the human electroencephalogram when the blood phenylalanine is raised three-fold - something that clearly will happen in children who consume near 5 servings per 50-pound body weight.
So if I may summarize, phenylalanine, is a known neurotoxin, and the food industry added nearly 8,000 tons of aspartame to the food supply in 1986, which amounts to approximately 8 million pounds of phenylalanine added to our food supply in a single year. |
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Brain cell damage from amino acid isolates (aspartame releases phenylalanine, aspartate, methanol [formaldehyde, formic acid] Bowen & Evangelista May 6 2002: Murray 11.10.3 rmforall, plain text http://groups.google.com/group/alt.support...6af1561aec25ee1| QUOTE | ....A can of soda pop yields about as much phenylalanine as a
large helping of beans.
NOTE: One 12 oz. can of diet soda contains 200 mg of aspartame.
Phenylalanine = 100 mg 50%
Aspartic Acid = 80 mg 40%
Methanol = 20 mg 10%
It should also be noted that the pharmaceutical isolates of amino acids
in aspartame are produced from genetically modified bacteria (E.coli).
About Phenylalanine
The dietary phenylalanine from the beans would only be harmful to the
person with PKU (phenylketonuria), an inherited genetic condition caused
by one of several enzyme deficiencies. This creates/allows increased
plasma levels of phenylalanine (overload), leading to the formation of
destructive neurotoxic effects.
In healthy individuals, the fact that dietary phenylalanine is in
competition with the other amino acids and is absorbed slowly over ten
to
twenty hours from the digestive tract, makes it helpful rather than
harmful for them.
In contrast, the phenylalanine (isolate) from the can of aspartame-laced
soda pop is absorbed in about five minutes. This goes to the portal vein
in the liver, with virtually no other competitive amino acids. Amino
acid
release from the liver is through an enzyme-linked channel. Without any
competition from any other amino acids, this phenylalanine is released
into the blood stream as an overwhelming bolus, or flood.
Even when ingested with foods, aspartame substantially increases the
plasma phenylalanine (and aspartic acid) levels, due to their
pharmaceutical make-up as isolates, and due to phenylalanine's strong
competitive affinity for the enzyme mediators and transmitter catalysts.
Synergistic damage also results from the absorption-metabolism sequence
of methanol, turned into formaldehyde and then formic acid. Methanol
and
formaldehyde are carcinogenic and mutagenic. As a metabolic poisons,
formaldehyde alters both mitochondrial DNA and nucleic DNA by binding as
adducts. This may be a strong initiator of disease states, because DNA,
damaged by formaldehyde adducts, may not allow cells to function
properly or maintain homeostasis. |
It continues...
| QUOTE | Following consumption of aspartame-laced products, the phenylalanine
flood overpowers the enzyme systems of the brain, setting off an induced
PKU effect.
This induced PKU affect occurs by grossly overwhelming those enzymes
required to reduce the circulating phenylalanine for use in other
metabolic reactions.
This "overdose" of the competitive phenylalanine isolate (and also
aspartic acid) incapacitates the enzyme actions which control several
types of neurotransmitters (and their precursor amino acids), reducing
dopamine and serotonin production.
The excitotoxins' effects create secondary components, which are also
destructive in nature to the sensitive, surrounding neural tissues,
including a breakdown by-product of phenylalanine, called
diketopiperazine
(DKP), which instigates tumor generation, especially that of aggressive
glioblastoma.
Further neuron insult is added due to the destruction and mutation of
nucleic and mitochondrial DNA from the known carcinogenic properties of
formaldehyde, from the methanol component of aspartame.
The other avenue of delivering nutrients and other necessary molecules
to the brain's cell structures is by way of the Cerebral Spinal Fluid
(CSF). |
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DLPA Dosing, How do I measure this stuff...
