I was talking to a football buddy of mine the other day and he said this past summer he had really great gains while taking 6-oxo alone, and just using it to boost his testosterone and not using roids or PHs or anything. Is there any truth to this, and is so, how much of an increase in strength and muscle are we talking?

It will increase testosterone so it should have benefits. Most think it is not worth the price and side effects (acne). See the 6-OXO sticky.