Aniracetam vs Piracetam

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Posted by: Dong38340 Aug 5 2004, 10:35 PM
I am looking at using one of these two products next semester to help me in my studying and test taking. Aniracetam is suppose to be far more potent but it has a very short half-life which I dont like. I want something that will aid me all day - from morning classes to late night studying. Piracetam defintily has a longer half-life but you need a higher dosage to get its effects. What would you guys reccomend?

Posted by: Dong38340 Aug 7 2004, 01:03 AM
Anyone??

Posted by: tintinet Aug 7 2004, 08:53 AM
I've not tried Aniracetam. I'm a bit wary of its possible potential for excitotoxicity. Piracetam, at least to me, appears to be a safer, more thoroughly tested nootropic.

Posted by: Geffen Aug 7 2004, 09:48 AM
Re: Aniracetam

For a period of one month, I was using a powerdrive/alcar/aniracetam stack. I found that during this time my short term memory had actually become an issue (never had been before). There were times when I would think about saying something to someone but after just a few seconds could not recall what I was thinking.
I discontinued usage of aniracetam (continued with powerdrive/alcar) and the problem has since gone away.
Not quite sure what to make of it but that's my experience with aniracetam.

My dosage with aniracetam:500mg/1x per day.

Posted by: lancelot Aug 7 2004, 11:39 AM
i didn't notice anything on piracetam at 3g/day for 4 months. But when i went on aniracetam at 500-700mg/day, my head started to feel heavy, fuzzy, and started to lack concentration. seems to work well for others, but not for me. i really recommend chocamine for a natural, safe, and more effective nootropic.

Posted by: shpongled Aug 7 2004, 10:05 PM
Going by feedback alone people do seem to report more mixed results from aniracetam. Some think it is a lot better and some worse than piracetam. My hunch is that it may just not work as well with some other supplements as piracetam does.

Posted by: M.36744 Aug 14 2004, 03:59 AM
Few years back I did use Piracetam 800mg/day for few weeks with Hydergine
4mg/day( i guess was 8 weeks) but did not notice a single thing, hydergine tough did give light headace but for the studies......nothing is better than the plain ol ephedrine HCL without the Guafi trash.

Posted by: ncinr8r Aug 16 2004, 03:57 PM
QUOTE (tintinet @ Aug 7 2004, 08:53 AM)
I've not tried Aniracetam. I'm a bit wary of its possible potential for excitotoxicity. Piracetam, at least to me, appears to be a safer, more thoroughly tested nootropic.

I'm interested in more information about Aniracetam and excitotoxicity. Where can I find more information about this?

Posted by: shpongled Aug 17 2004, 04:29 AM
Read the article below. I do not think it is a significant concern.

I also posted this elsewhere:

1. Aniracetam does not directly stimulate AMPA receptors - instead, it slows the rate of desensitization/deactivation in the presence of an agonist, thus amplifying long-term potentiation. It does this allosterically, in other words, it does not directly act at the binding site. It only has an effect in the presence of an agonist. So you can't really compare it to an excitotoxin.

2. Aniracetam is selective at certain types of AMPA receptors, in certain areas of the brain.

3. Aniracetam-induced AMPA receptor activation --> kainate receptor desensitization, serving as a negative feedback mechanism. It is possible that this actually leads to a net reduction of excitotoxicity, since, as mentioned previously, aniracetam does not act as an agonist.

4. One of the metabolites of aniracetam positively modulates group II metabotropic glutamate receptors, and some subtypes of mGlu reduce excitotoxicity.

5. The metabolites of aniracetam have many other effects that could potentially counteract any possible excitotoxicity. Accordingly, the majority of the research shows aniracetam to prevent excitotoxicity. Instead of theories, we actually have information on the endpoint, which on balance is in favor of aniracetam acting as a neuroprotectant.

Posted by: William81195 Jul 29 2005, 06:41 PM
QUOTE (tintinet @ Aug 7 2004, 08:53 AM)
I've not tried Aniracetam. I'm a bit wary of its possible potential for excitotoxicity. Piracetam, at least to me, appears to be a safer, more thoroughly tested nootropic.

try taking GABA to balance the increase in glutamine transmition... I take 200mg in the AM and 2-3000mg at night... It makes dreams more vivid, for me at least.
I am on aniracetam and piracetam and just added oxiracetam... I take lecithin and dmae, and other various... Try GABA... definitely.(for memory, intelligent thought)(gaba is required to release glutamate in all instances)

Posted by: Meta_frame May 4 2006, 04:00 PM
Personally I feel that their are not defined mechanisms or clear research showing that aniracetam does or does not cause excitotoxicity. That said... I have personally used it for a period of time, and absolutely did NOT like it. Noticed significant drops in my memory performance both short and long term. While this is only my personal experience, I feel its important to share. On a side note I DO receive significant improvements using piracetam.

Posted by: michael74932 May 5 2006, 12:42 PM
From what I have heard (other's research) Aniracetam will not cause damage (that would not make sence anyways because of the category it resides in), I guess that goes along the same lines of DMAE, some research makes it out to sound like it is bad, which in most cases is just not true. Personally Piracetam does nothing which I can note as stimulating (or obvious) for me, so I cannot say if it works or not, but it is supposedly proven to help retain memory,and function over the years. Aniracetam for a while worked wonders on my ability, anxiety, and memory, I was pretty much overall more "aware" and confident. The only bad factor with the Aniracetam was, like all other products I take, I needed to use the high scale of recommendation, which cost wise adds up. That and the second time I purchased it, for some odd reason, I no longer felt an effect.

Posted by: bla2d2 Oct 8 2006, 12:59 PM
I haven't tried the aniracetam but have been very pleased with the piracetam. Takin in 7 gram doses 3 times a day seems to do the trick nicely. I feel more relaxed yet aware. I become chatty kathy though and tend to go into much more detail than before. It also seems to increase my use of vocabulary words that I know the definitions to but never seem to remember to fit them into my everyday chatter. Seems to elevate my mood perhaps this is because I am happy with the initial effects. I give Piracetam a thumbs up. P.S. Goes great with a healthy dose of Phenibut..

Posted by: jackrabbit Oct 18 2006, 02:20 PM
QUOTE (bla2d2 @ Oct 8 2006, 12:59 PM)
I haven't tried the aniracetam but have been very pleased with  the piracetam.  Takin in 7 gram doses 3 times  a day seems to do the trick nicely.  I feel more relaxed yet aware.  I become chatty kathy though and tend to go into much more detail than before.  It also seems to increase my use of  vocabulary words that I know the definitions to but never seem to remember to fit them into my everyday chatter.  Seems to elevate my mood perhaps this is because I am happy with the initial effects.  I give Piracetam a thumbs up.  P.S.  Goes great with a healthy dose of Phenibut..


7g x 3 = 21 g/day which is pretty hefty for piracetam from what I have read. I am using ~2.4g x 2-3 times/day stacked with 3g of choline citrate x 1/day. Research the attack dose when using nootropics; ie. you may need to take 2 or 3 times the normal dosing the first time (and sometimes for a few days) before resorting to a normal dose. Your normal dose is dependant on your desired effects which you can find in a good matrix of grams to effect (on this site and others). If using as a powder, mix with OJ until you are used to the taste. I mix a shot-sized amount of water with the dose and take it in one gulp.

Posted by: Nika51 Oct 18 2006, 10:32 PM
I'm thinking about piracetam powder, but then I looked up Focus XT. Can you take either of these products while on creatine? Does the caffeine in FXT affect the creatine?

Posted by: RepubCarrier Oct 19 2006, 12:17 AM
creatine and caffeine are not a problem. Creatine, piracetam, and caffeine are all neuroactive, but at most I would expect a slight potentiation of caffeine's effect, and it is most like likely that you'll notice no interaction effects.

Piracetam definetely has an effect on me. It is most noticeable after a night of heavy drinking when my mind is still foggy. Aniracetam has negative effects on me (I can't speak properly) at any dose above 400-500mg. I tried using 1g Pir + 100mg Ani for a few weeks, but I could not even be sure the ani was adding much to this, so I stopped using it.

Posted by: Debaser Oct 19 2006, 11:20 AM
what is the shelf life of Piracetam? I bought some here 2 years ago and still haven't finished it. Also, can I take it if I am taking Ritalin?

I only use piracetam for the creativity it brings me

Posted by: RepubCarrier Oct 19 2006, 08:27 PM
QUOTE (Debaser @ Oct 19 2006, 11:20 AM)
what is the shelf life of Piracetam? I bought some here 2 years ago and still haven't finished it. Also, can I take it if I am taking Ritalin?

I only use piracetam for the creativity it brings me

be careful of ritalin increasing in strength. there are widespread reports of certain chemicals being potentiated by piracetam, namely MDMA. While ritalin doesn't look much like MDMA chemically, I simply don't know which drugs (if any, in reality) are affected in this way and which are not.

Posted by: bla2d2 Oct 29 2006, 09:56 AM
QUOTE (jackrabbit @ Oct 18 2006, 02:20 PM)
QUOTE (bla2d2 @ Oct 8 2006, 12:59 PM)
I haven't tried the aniracetam but have been very pleased with  the piracetam.   Takin in 7 gram doses 3 times  a day seems to do the trick nicely.   I feel more relaxed yet aware.   I become chatty kathy though and tend to go into much more detail than before.   It also seems to increase my use of  vocabulary words that I know the definitions to but never seem to remember to fit them into my everyday chatter.   Seems to elevate my mood perhaps this is because I am happy with the initial effects.   I give Piracetam a thumbs up.   P.S.  Goes great with a healthy dose of Phenibut..


7g x 3 = 21 g/day which is pretty hefty for piracetam from what I have read. I am using ~2.4g x 2-3 times/day stacked with 3g of choline citrate x 1/day. Research the attack dose when using nootropics; ie. you may need to take 2 or 3 times the normal dosing the first time (and sometimes for a few days) before resorting to a normal dose. Your normal dose is dependant on your desired effects which you can find in a good matrix of grams to effect (on this site and others). If using as a powder, mix with OJ until you are used to the taste. I mix a shot-sized amount of water with the dose and take it in one gulp.

Thanks for the advice I took this max dose (7gx3 a day for five days) and just read your response. I will take this advice and back off my milligram intake throughout the day. I also just got my first jar of aniracetam. Took my first dose this morning. I took a 1000 mg with difficulty because it didn't want to dissolve in my water. I had to shake vigorously and rerinse the bottle over and over to get it all ingested. Any advice on dosing levels for stacking aniracetam and piracetam, and how do you administer aniracetam since it is apparantly not very water soluble?

Posted by: Wesley111276 Dec 30 2006, 05:44 AM
I've had much benefit from taking any racetam. I took Piracetam 2.5gm a day w/triple lecithin for approx. 4 months. I noticed a change in thinking after 2 weeks. As a musician I noticed my creative ability to improvise was more affluent. Now I'm taking Aniracetam 750mg 2X daily w/triple lecithin, fish oils, & a multi. This racetam has a very different effect on me as opposed to Piracetam. My memory has improved dramatically, creativeness enhancement is stronger, my attention span has increased, & I tend to choose wording more carefully in order to get the desired message/response. Noticed that I hear everything without even focusing. Listening to music & playing music is much more enjoyable. Reading & typing speed increased. One downside is that I tend to require more sleep probably due my brain taking in more information, not necessarily working faster. Dreams are more vivid & I seem to remember almost all of them. I am very impressed with aniracetam & will continue to use it in cycles of course. I believe any supplement or drug will create a different effect on each individual due simply to the fact that everyone is different. I can not drink alcohol when I have been taking aniracetam though. After about 6 or 7 drinks it causes me to fall asleep wherever I may be (even while walking!) I now know what it is like to have Narcolepsy. Has anyone else experienced this phenomena?

Posted by: jackrabbit Mar 18 2007, 06:19 PM
QUOTE (bla2d2 @ Oct 29 2006, 09:56 AM)
QUOTE (jackrabbit @ Oct 18 2006, 02:20 PM)
QUOTE (bla2d2 @ Oct 8 2006, 12:59 PM)
I haven't tried the aniracetam but have been very pleased with  the piracetam.  Takin in 7 gram doses 3 times  a day seems to do the trick nicely.  I feel more relaxed yet aware.  I become chatty kathy though and tend to go into much more detail than before.  It also seems to increase my use of  vocabulary words that I know the definitions to but never seem to remember to fit them into my everyday chatter.  Seems to elevate my mood perhaps this is because I am happy with the initial effects.  I give Piracetam a thumbs up.  P.S.  Goes great with a healthy dose of Phenibut..


7g x 3 = 21 g/day which is pretty hefty for piracetam from what I have read. I am using ~2.4g x 2-3 times/day stacked with 3g of choline citrate x 1/day. Research the attack dose when using nootropics; ie. you may need to take 2 or 3 times the normal dosing the first time (and sometimes for a few days) before resorting to a normal dose. Your normal dose is dependant on your desired effects which you can find in a good matrix of grams to effect (on this site and others). If using as a powder, mix with OJ until you are used to the taste. I mix a shot-sized amount of water with the dose and take it in one gulp.

Thanks for the advice I took this max dose (7gx3 a day for five days) and just read your response. I will take this advice and back off my milligram intake throughout the day. I also just got my first jar of aniracetam. Took my first dose this morning. I took a 1000 mg with difficulty because it didn't want to dissolve in my water. I had to shake vigorously and rerinse the bottle over and over to get it all ingested. Any advice on dosing levels for stacking aniracetam and piracetam, and how do you administer aniracetam since it is apparantly not very water soluble?

I have not used Aniracetam, but am currently considering switching from Piracetam to it. I don't think I would take both at the same time as I believe there is wisdom in knowing there can be too much of a good thing. Right now, I think I'm going to stick with the Piracetam, although I am curious about Ani. I'll let you know what I think if I switch. However, Aniracetam is lipid soluble according to what I've read. Fats are a category of lipids and one such example of fats are the Omega's. I am purely hypothesizing as I haven't seen this anywhere before and I certainly am not qualified to say for sure, but possibly you could get a flax seed oil (non-pill form) and mix the two. I'd appreciate if anyone has feedback on this because I'm wondering even if stacking a lipid and ani will increase its bio-availability somehow.

Posted by: Debaser Jun 21 2007, 01:06 PM
Anyone from BN give me an answer on Piracetam shelf life? I guess Ill just start taking it again and see. I have a ton of this crap left....I shouldnt say crap, because this stuff is a God send.

Posted by: Nanook Jul 4 2007, 02:34 AM
QUOTE (RepubCarrier @ Oct 19 2006, 08:27 PM)
QUOTE (Debaser @ Oct 19 2006, 11:20 AM)
what is the shelf life of Piracetam?  I bought some here 2 years ago and still haven't finished it.  Also, can I take it if I am taking Ritalin?

I only use piracetam for the creativity it brings me

be careful of ritalin increasing in strength. there are widespread reports of certain chemicals being potentiated by piracetam, namely MDMA. While ritalin doesn't look much like MDMA chemically, I simply don't know which drugs (if any, in reality) are affected in this way and which are not.

I have used both together. I have seen no change in the effect of Ritalin with Piracetam, not positive nor negative. I was hoping that they might be synergistic since both by themselves seem to improve focus and concentration. Unfortunately, while Piracetam was helpful by itself and Ritalin was helpful by itself, the effect of both taken together does not seem to be either quantitatively or qualitatively different than Ritalin alone.

Posted by: Drakuun Mar 31 2008, 05:39 AM
Anyone tried Pramiracetam (Neupramir or Pramistar)?

Do those Racetams have any sleep deprivation effect or can they be taken before going to sleep?

Posted by: cogno418 Apr 11 2008, 11:01 AM
Well hers what aniracetam did for me in the recommended dosage for 3 weeks straight:
Bad bad pumps (bad in the sense of shitty) , like a loss of motivation and juice after like 3-4 reps and thats not normal for me.
Red face, but thats chill...
Mixed wit a high dose of phenibut it made me have a mini seizure , shitty.
The ONLY good point i saw is that when i was working i had no problemo handling 4 tasks at the same and that in a stressful situation.
verdict: Keep yer money this is not a noo-tropic its stupid.

Posted by: smartmart May 7 2008, 08:36 PM
ive had wonderous results using about 2400mg piracetam ,750mg aniracetam ,3600mg of lecithin ,300mg alpha gpc,250mg cdp choline, 400mg ALC+200mg ALA,90mg idebenone,500mg centrophenoxine,all two times a day plus 4.5mg hydergine once.

Posted by: smartmart May 7 2008, 08:37 PM
ive had wonderous results using about 2400mg piracetam ,750mg aniracetam ,3600mg of lecithin ,300mg alpha gpc,250mg cdp choline, 400mg ALC+200mg ALA,90mg idebenone,500mg centrophenoxine,all two times a day plus 4.5mg hydergine once.

Posted by: TheDiesel May 8 2008, 11:06 AM
QUOTE (shpongled @ Aug 17 2004, 04:29 AM)
Read the article below. I do not think it is a significant concern.

I also posted this elsewhere:

1. Aniracetam does not directly stimulate AMPA receptors - instead, it slows the rate of desensitization/deactivation in the presence of an agonist, thus amplifying long-term potentiation. It does this allosterically, in other words, it does not directly act at the binding site. It only has an effect in the presence of an agonist. So you can't really compare it to an excitotoxin.

2. Aniracetam is selective at certain types of AMPA receptors, in certain areas of the brain.

3. Aniracetam-induced AMPA receptor activation --> kainate receptor desensitization, serving as a negative feedback mechanism. It is possible that this actually leads to a net reduction of excitotoxicity, since, as mentioned previously, aniracetam does not act as an agonist.

4. One of the metabolites of aniracetam positively modulates group II metabotropic glutamate receptors, and some subtypes of mGlu reduce excitotoxicity.

5. The metabolites of aniracetam have many other effects that could potentially counteract any possible excitotoxicity. Accordingly, the majority of the research shows aniracetam to prevent excitotoxicity. Instead of theories, we actually have information on the endpoint, which on balance is in favor of aniracetam acting as a neuroprotectant.

Good info.

Posted by: rtjloco May 9 2008, 03:48 PM
Hi,

I am about to start takeing piracetam with choline bitartrate. I will experiment with the doses. My question is - I currently take 5htp 100mg before bed as it appears to help with my mood and general well being. Does anyone have any info on whether this could cause any problems with piraacetam. I also take a dose of creatine ether 3g each morning and sometimes L glutamine though I understand this is not a problem. Any info would be appreciated. Thanks

Posted by: Hoeward Jun 3 2008, 01:34 AM
Did piracetam make short -term memory worse for any of you? I've been on it for about 4 days and it seems like I tend to forget thigs I've done 2 mins ago. I rarely have this. Does this mean I should stop or is this a phase I have to get through? Does this get better?

Posted by: Jason97 Jun 28 2008, 08:33 PM
Every day that goes by, I'm becoming more and more enamoured with my new love: Piracetam! Because rather than tolerance making the doses less effective, I am finding them to last longer and longer. At first I would start getting a bit of mental tiredness about one hour before the next dose (I admit stretching the doses over way too long a time period - 5-5.5 hours instead of 4). Now I don't even notice a drop in the clarity or awakeness before my next dose.

In other words, this stuff is making lasting, functional changes to my brain, which means I just don't get mentally tired like I used to.

Its been eight days, but not once have I felt tired, at any moment in my waking hours, even at the end of long days of work and after repeated 2.00am nights. Yes, this stuff is God in powdered form, truly. My life is now clear, sharp, alert. Before I would get so tired working on my PC in the afternoons, I would constantly be falling into microsleeps. It was terrible. Btw. I've never used any caffeine or alcohol or prescription stimulants.

Best, no matter how late the dose, I can work 'till whatever hour then flop into bed and go to sleep right away. It doesn't interfere in the least with sleep, in fact sleep is deeper and more refreshing than ever, with significantly more brilliant dreams.

I did have to start eating egg yolks, due to the appearance on day three of an extremely mild headache (barely noticeable). Within two hours after eating six egg yolks, it was gone, permanently. I'm currently eating six raw egg yolks per day, and will cut back to four shortly. They're delicious, too.

I take 3 teaspoons a day, at these times:

1. 9.00a (or whenever I get up)
2. 4.00p
3. 9.00p

I'm just so amazed how my brain can really perform. This stuff is the most truly magical compound. The closest to a total genetic re-engineering of the brain, without having to do so.

Even better, it potentiates cannabis significantly for me (2x) and decreases negative side-effects!

Posted by: AdamGrossman Jun 28 2008, 08:59 PM
Holy piracetam spokesman...