2-4 total. Unless a product is specifically aimed towards one or the other, they usually contain them in the same ratio.
Here is a section from my
fish oil article, the full text is linked at the bottom.
Fish oil consumption is generally safe and well tolerated, with less adverse effects than other dietary oils [12]. Doses equivalent to three times the FDA maximum safe dosage (which is 3 g EPA/DHA per day) appear to be safe in rats [39]. The primary reported side effect is "fish burps" or a "fishy taste in the mouth," although this can depend on the product, and it is also commonly reported to only be a problem for the first few weeks of
fish oil consumption. However there are a few more serious side effects that may be seen with high dose
fish oil consumption which may warrant caution.
The first of these is that high doses of
fish oil may decrease immune function (in opposition to lower intakes, which may enhance it) [40-42]. While this is beneficial in some autoimmune diseases it is not always desirable. For example, high amounts of
fish oil may impair bacterial resistance [43]. Modest doses, in the range of 1-2 g of EPA/DHA daily, do not appear to have a negative impact on immune function over 6 months [40]. This effect may also be avoided with supplemental
vitamin E [42]. A second potential problem is increased lipid peroxidation, resulting in an increase in oxidative stress [44-47]. However, this effect can also be remedied with
vitamin E [9, 48].
Another possible side effect is an increase in LDL cholesterol and a decrease in HDL cholesterol [49-50]. The first of these effects can be seen with doses as low as 3.6 g/day in humans [49]. However, LDL increase is generally less than 5% [16], and
fish oil on balance has a very positive impact on the cardiovascular system. Since
fish oil thins the blood, it may also increase the likelihood of bleeding, but it does not appear to do this at lower doses. 2-5 grams a day, even when combined with other blood thinners such as aspirin, do not appear to increase bleeding time, but intake over 20 grams a day will increase bleeding times [16]. Other possible side effects of high or very high dose
fish oil consumption reported in animals are increased liver and spleen weight, adverse effects on iron metabolism, and red blood cell deformities [45, 46, 50], but it is doubtful that these are relevant in moderate doses.
What all of this amounts to is,
fish oil consumption in a healthy individual should probably be kept within a reasonable range, and additional supplementation with
vitamin E is also a good choice. The amount of
fish oil one takes should be dependent on both goals and the amount of EPA/DHA present in the
fish oil. The optimal range for both safety and effectiveness in most healthy individuals is 1-4 g of EPA/DHA daily, and this amount shouldn't be exceeded without medical supervision. Most fish oils are standardized to 30% EPA/DHA, so this would be about 3-12 one gram caps daily. If the
fish oil is standardized to a different amount the dosage should be changed accordingly, for example 2-8 caps of a 50% EPA/DHA product. Most of the benefits (other than possibly the change in body composition, for which there is presently little functional data) can be seen with 1-2 grams of EPA/DHA daily. Most
fish oil capsules also contain
vitamin E, but if they don't, a
vitamin E supplement should be taken also.